Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354437 | 1.00 | LMNA (0.48) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28348147 | 0.87 | LMNA (0.44) | LMNAPOLBGAADGAT1BACE1 | |
| SCHEMBL28350831 | 0.83 | ACACB (0.34) | LMNAPOLBKLKB1 | |
| SCHEMBL28354293 | 0.83 | ACACB (0.34) | LMNAPOLBKLKB1 | |
| SCHEMBL28354213 | 0.79 | LMNA (0.45) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28350366 | 0.79 | LMNA (0.45) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28350657 | 0.78 | LMNA (0.47) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28350722 | 0.78 | LMNA (0.47) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28350304 | 0.76 | LMNA (0.42) | LMNAPOLBGAADGAT1STING1 | |
| SCHEMBL28958595 | 0.76 | LMNA (0.42) | LMNAPOLBGAADGAT1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110734403-B | (S) -2- (1H-pyrazole-4-formamido) propyl benzoate compound and preparation method and application thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-110734403-A | (S) -2- (1H-pyrazole-4-formamido) propyl benzoate compound and preparation method and application thereof | 浙江工业大学 | 2020-01-31 | — | — | CN | disclosed |