SCHEMBL28354512

SCHEMBL28354512

C=CC(=O)OCC([SiH3])Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 1/20 0.43
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
CYP1A2 P05177 1/20 0.41
SRR Q9GZT4 2/20 0.39
SLC1A3 P43003 2/20 0.39
SLC1A2 P43004 2/20 0.39
SLC1A1 P43005 2/20 0.39
HCAR2 Q8TDS4 1/20 0.38
SLC15A1 P46059 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MDM2 Q00987 1/20 0.38
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26840962 0.84 THRB (0.49) THRBTSHRALPIPKMPTGS1
SCHEMBL1637392 0.83 THRB (0.47) THRBTSHRALPIPKMPTGS1
SCHEMBL5467970 0.81 TSHR (0.51) THRBTSHRCYP1A2ALDH1A1CYP3A4
SCHEMBL27585813 0.80 CYP1A2 (0.49) THRBTSHRALPIPKMPTGS1
SCHEMBL22195196 0.79 PPARG (0.46) THRBTSHRALPIPKMPTGS1
SCHEMBL12317444 0.77 CTSL (0.50) THRBTSHRALDH1A1CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL1683545 0.77 TSHR (0.42) THRBTSHRALDH1A1
SCHEMBL10182523 0.77 CTSL (0.50) THRBTSHRALDH1A1CYP3A4CYP2C9
SCHEMBL2399074 0.77 CTSL (0.50) THRBTSHRALDH1A1CYP3A4CYP2C9
SCHEMBL15309909 0.76 TSHR (0.41) THRBTSHRCYP1A2SRRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110785159-A Dual paste type dental curable composition 可乐丽则武齿科株式会社 2020-02-11 CN disclosed