SCHEMBL28355153

SCHEMBL28355153

CC1(C)C=CC=CC1Cc1ccccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.40
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
KMT2A Q03164 1/20 0.35
CYP26A1 O43174 1/20 0.33
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
HTR7 P34969 3/20 0.31
FOLH1 Q04609 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
KCNA5 P22460 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL29214451 0.74 SLC22A2 (0.31) SLC6A4
SCHEMBL29695832 0.72 KDM4E (0.34) KMT2A
SCHEMBL29723846 0.71 PTPN1 (0.55) FOLH1
SCHEMBL15673020 0.70 BRD4 (0.35) HTR7CYP11B2
SCHEMBL29261424 0.68 KDM4E (0.33) KMT2A
SCHEMBL28502561 0.65 TSHR (0.36)
SCHEMBL28358368 0.65 PTGS2 (0.42) DPP4PDCD1CD274KMT2ASLC6A2
SCHEMBL28667819 0.62 ALDH1A1 (0.40) KMT2A
SCHEMBL75518 0.62 KDM1A (0.35) CA1CA2
SCHEMBL31261742 0.62 DPP4 (0.60) DPP4PDCD1CD274KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643095-A Preparation method of oil-resistant acid-base-resistant sealing ring 广东瑞福密封科技有限公司 2020-01-03 CN claimed
CN-110643095-A Preparation method of oil-resistant acid-base-resistant sealing ring 广东瑞福密封科技有限公司 2020-01-03 CN disclosed