SCHEMBL28355209

SCHEMBL28355209

CCOCCOCOCCOC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.39
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4957828 0.94
SCHEMBL27995200 0.92 CA2 (0.34) ALDH1A1TSHRCA2KDM4ERECQL
SCHEMBL23054396 0.92 ALDH1A1 (0.33) ALDH1A1TSHRCA2
SCHEMBL1081604 0.91 ALDH1A1 (0.47) ALDH1A1TSHRTHRBCA2KDM4E
SCHEMBL12228 0.91
SCHEMBL6753265 0.91 ALDH1A1 (0.47) ALDH1A1TSHRTHRBCA2KDM4E
SCHEMBL14770369 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTHRBCA2KDM4E
SCHEMBL16546828 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTHRBCA2KDM4E
SCHEMBL4512442 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTHRBCA2KDM4E
SCHEMBL9567053 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTHRBCA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114981331-B Linear polymers containing isocyanate groups SIKA技术股份公司 2025-02-11 CN disclosed
CN-117887023-A Isocyanate group-containing polymers with low content of monomeric diisocyanates SIKA技术股份公司 2024-04-16 CN disclosed
CN-112543779-B Isocyanate group-containing polymers with low content of monomeric diisocyanates SIKA技术股份公司 2024-04-05 CN disclosed
CN-117355551-A Reducing the content of monomeric polyisocyanates in polyurethane compositions SIKA技术股份公司 2024-01-05 CN disclosed
CN-110753694-B Aldiminosilanes SIKA技术股份公司 2023-07-14 CN disclosed
CN-112533972-B Polyurethane compositions with low levels of monomeric diisocyanates SIKA技术股份公司 2023-05-23 CN disclosed
CN-114981331-A Linear polymers containing isocyanate groups SIKA技术股份公司 2022-08-30 CN disclosed
CN-110770272-B Latent curing agent and curable polyurethane composition SIKA技术股份公司 2022-03-29 CN disclosed
CN-112543779-A Isocyanate group-containing polymers having a low content of monomeric diisocyanates SIKA技术股份公司 2021-03-23 CN disclosed
CN-112533972-A Polyurethane compositions with low content of monomeric diisocyanates SIKA技术股份公司 2021-03-19 CN disclosed
CN-110770272-A Latent curing agent and curable polyurethane composition SIKA技术股份公司 2020-02-07 CN disclosed
CN-110753694-A Aldiminosilanes SIKA技术股份公司 2020-02-04 CN disclosed