Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355289 | 0.84 | IDO1 (0.67) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11607091 | 0.83 | IDO1 (0.52) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6323640 | 0.73 | IDO1 (0.53) | IDO1NPC1RAB9ASMN1; SMN2ALOX12 | |
| SCHEMBL11609702 | 0.73 | IDO1 (0.46) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2794397 | 0.73 | IDO1 (1.00) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13554435 | 0.72 | PTGS1 (0.66) | NPC1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL10936011 | 0.71 | IDO1 (0.55) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11609701 | 0.71 | MGLL (0.56) | NPC1RAB9AALDH1A1CA12CA1 | |
| SCHEMBL6319495 | 0.71 | IDO1 (0.51) | IDO1SMN1; SMN2ALDH1A1ALOX12LMNA | |
| SCHEMBL11608898 | 0.70 | TEAD4 (0.50) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076814-A | DITHIOCARBAMIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JA) | 1978-02-28 | — | — | US | disclosed |