Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.60 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103701 | 0.86 | L3MBTL3 (0.62) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL28352248 | 0.82 | HPGD (0.63) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL28355798 | 0.81 | HPGD (0.69) | HPGDTSHRL3MBTL1L3MBTL3ALDH1A1 | |
| SCHEMBL6554857 | 0.79 | HPGD (0.71) | HPGDTSHRL3MBTL1L3MBTL3ALDH1A1 | |
| SCHEMBL20516444 | 0.79 | HPGD (0.71) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL2376496 | 0.76 | HPGD (0.77) | HPGDTSHRALDH1A1RECQLCYP1A2 | |
| SCHEMBL2378485 | 0.76 | HPGD (0.77) | HPGDTSHRALDH1A1RECQLCYP1A2 | |
| SCHEMBL31533277 | 0.76 | HPGD (0.63) | HPGDTSHRALDH1A1RECQLCYP1A2 | |
| SCHEMBL971662 | 0.76 | HPGD (0.63) | HPGDTSHRALDH1A1RECQLCYP1A2 | |
| SCHEMBL1353095 | 0.76 | HPGD (0.63) | HPGDTSHRALDH1A1RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110759889-B | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2022-05-20 | — | — | CN | disclosed |
| CN-110759889-A | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2020-02-07 | — | — | CN | disclosed |