Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25727724 | 0.88 | KMT2A (0.49) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL5103932 | 0.87 | MBTD1 (0.56) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL28355609 | 0.83 | HPGD (0.61) | HPGDTSHRALDH1A1KDM4EGAA | |
| SCHEMBL28355482 | 0.82 | HPGD (0.66) | HPGDTSHRL3MBTL1MBTD1L3MBTL3 | |
| SCHEMBL20456915 | 0.79 | L3MBTL3 (0.59) | HPGDL3MBTL1L3MBTL3ALDH1A1KDM4E | |
| SCHEMBL4002578 | 0.79 | HPGD (0.69) | HPGDL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL23675251 | 0.79 | HPGD (0.71) | HPGDTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL70233 | 0.78 | KDM4E (0.62) | HPGDALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL27301539 | 0.77 | KMT2A (0.48) | ALDH1A1KDM4EGAAKMT2AGLA | |
| SCHEMBL70433 | 0.77 | HPGD (0.69) | HPGDL3MBTL1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110759889-B | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2022-05-20 | — | — | CN | disclosed |
| CN-110759889-A | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2020-02-07 | — | — | CN | disclosed |