Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634802 | 0.86 | TSHR (0.56) | TP53TSHRALDH1A1LMNASLC7A5 | |
| Lactic Acid SCHEMBL28194184 | 0.84 | TP53 (0.58) | TP53TSHRALDH1A1SLC7A5TET2 | |
| L-Lactic Acid SCHEMBL29395214 | 0.83 | TP53 (0.65) | TP53TSHRALDH1A1LMNA | |
| Lactic Acid SCHEMBL18398168 | 0.83 | TP53 (0.65) | TP53TSHRALDH1A1LMNA | |
| Lactic Acid SCHEMBL453357 | 0.83 | TP53 (0.65) | TP53TSHRALDH1A1LMNA | |
| Lactic Acid SCHEMBL16555873 | 0.80 | TP53 (0.69) | TP53TSHRALDH1A1LMNASLC7A5 | |
| Lactic Acid SCHEMBL28274824 | 0.80 | — | — | |
| Lactic Acid SCHEMBL1517824 | 0.80 | — | — | |
| SCHEMBL2014114 | 0.80 | ALDH1A1 (0.62) | TP53TSHRALDH1A1 | |
| Acetic Acid SCHEMBL11440462 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110683945-A | Method for preparing lactic acid by catalytic hydrolysis of isoamyl lactate | 华东理工大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-110683945-A | Method for preparing lactic acid by catalytic hydrolysis of isoamyl lactate | 华东理工大学 | 2020-01-14 | — | — | CN | disclosed |