SCHEMBL28356346

SCHEMBL28356346

FC(F)C1CCC2CCCCC2C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360330 0.84 ALDH1A1 (0.44) ALDH1A1
SCHEMBL595187 0.75 ALDH1A1 (0.40) ALDH1A1IDO1TDO2
SCHEMBL3003466 0.75 ALDH1A1 (0.40) ALDH1A1IDO1TDO2
SCHEMBL2993539 0.75 ALDH1A1 (0.40) ALDH1A1IDO1TDO2
SCHEMBL14632242 0.75 ALDH1A1 (0.40) ALDH1A1IDO1TDO2
SCHEMBL29254014 0.71 ALDH1A1 (0.36) ALDH1A1
SCHEMBL2991559 0.71 ALDH1A1 (0.67) ALDH1A1
SCHEMBL6688258 0.71 ALDH1A1 (0.67) ALDH1A1
SCHEMBL5130827 0.70 IDO1 (0.33) ALDH1A1IDO1TDO2
SCHEMBL22037123 0.70 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110655539-B Method for synthesizing cis-difluoromethylcyclohexane derivatives and heterocyclic compounds by hydrogenation 四川大学 2021-11-12 CN disclosed
CN-110655539-A Method for synthesizing cis-difluoromethylcyclohexane derivatives and heterocyclic compounds by hydrogenation 四川大学 2020-01-07 CN disclosed