SCHEMBL28360330

SCHEMBL28360330

FC(F)C1CCC(C2CCCCC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28356346 0.84 ALDH1A1 (0.40) ALDH1A1
SCHEMBL1030917 0.82
SCHEMBL3017648 0.82 EPHX1 (0.41) ALDH1A1
SCHEMBL3018849 0.82 EPHX1 (0.41) ALDH1A1
SCHEMBL3006612 0.78
SCHEMBL10750 0.78
SCHEMBL17550031 0.76
SCHEMBL13767780 0.76
SCHEMBL19502509 0.76 SHBG (0.41)
SCHEMBL9607854 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110655539-B Method for synthesizing cis-difluoromethylcyclohexane derivatives and heterocyclic compounds by hydrogenation 四川大学 2021-11-12 CN disclosed
CN-110655539-A Method for synthesizing cis-difluoromethylcyclohexane derivatives and heterocyclic compounds by hydrogenation 四川大学 2020-01-07 CN disclosed