SCHEMBL28356386

SCHEMBL28356386

CC(CCl)C1=NCCN1CCO

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.36
TOP2B Q02880 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9659510 0.83 TOP2A (0.38) TOP2ATOP2B
SCHEMBL224097 0.82 TOP2A (0.40) TOP2ATOP2B
SCHEMBL5496738 0.82 TOP2A (0.35) TOP2ATOP2B
SCHEMBL5496734 0.82 TOP2A (0.35) TOP2ATOP2B
Hydrochloric Acid SCHEMBL16262503 0.81 TOP2A (0.42) TOP2ATOP2B
Hydrochloric Acid SCHEMBL535313 0.81 TOP2A (0.42) TOP2ATOP2B
SCHEMBL18298166 0.81 TOP2A (0.39) TOP2ATOP2B
Hydrochloric Acid SCHEMBL28347496 0.81 TOP2A (0.42) TOP2ATOP2B
Hydrochloric Acid SCHEMBL818510 0.81 TOP2A (0.38) TOP2ATOP2B
Hydrochloric Acid SCHEMBL29829553 0.81 TOP2A (0.38) TOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459304-B Process for preparing water-soluble homo-or copolymers comprising (meth) acrylamide 巴斯夫欧洲公司 2020-02-07 CN disclosed