Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A known ✓ | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B known ✓ | Q02880 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28347496 | 1.00 | TOP2A (0.42) | TOP2ATOP2BALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL16262503 | 1.00 | TOP2A (0.42) | TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL224097 | 0.98 | TOP2A (0.40) | TOP2ATOP2B | |
| SCHEMBL18298166 | 0.85 | TOP2A (0.39) | TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL29829553 | 0.82 | TOP2A (0.38) | TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL818510 | 0.82 | TOP2A (0.38) | TOP2ATOP2B | |
| SCHEMBL28356386 | 0.81 | TOP2A (0.36) | TOP2ATOP2B | |
| SCHEMBL5496738 | 0.80 | TOP2A (0.35) | TOP2ATOP2B | |
| SCHEMBL5496734 | 0.80 | TOP2A (0.35) | TOP2ATOP2B | |
| SCHEMBL9659510 | 0.76 | TOP2A (0.38) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976151-B2 | Polymer polyol and process for producing the same | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2024-05-07 | — | — | US | claimed |
| CN-117510701-A | Water-absorbent resin particle, preparation method thereof and absorber | 中国天辰工程有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117264132-A | Polymer polyol and process for producing the same | 锦湖石油化学株式会社 | 2023-12-22 | — | — | CN | claimed |
| US-20230399449-A1 | POLYMER POLYOL AND PROCESS FOR PRODUCING THE SAME | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2023-12-14 | — | — | US | claimed |
| CN-110498912-B | Curable unsaturated crystalline polyester powder and process for preparing the same | 施乐公司 | 2023-09-01 | — | — | CN | claimed |
| EP-3569634-B1 | CURABLE UNSATURATED CRYSTALLINE POLYESTER POWDER AND METHODS OF MAKING THE SAME | XEROX CORP (US) | 2023-04-19 | — | — | EP | claimed |
| EP-3732145-A1 | METHOD FOR CONTROLLING THE PERMEABILITY OF A PETROLEUM WELL | Eni S.p.A. (IT) | 2020-11-04 | — | — | EP | claimed |
| CN-111655651-A | Method for controlling permeability of a petroleum well | 埃尼股份公司 | 2020-09-11 | — | — | CN | claimed |
| US-10703859-B2 | Compositions comprising unsaturated crystalline polyester for 3D printing | XEROX CORPORATION (US) | 2020-07-07 | — | — | US | claimed |
| US-10655025-B2 | Curable unsaturated crystalline polyester powder and methods of making the same | XEROX CORPORATION (US) | 2020-05-19 | — | — | US | claimed |
| US-20190352455-A1 | COMPOSITIONS COMPRISING UNSATURATED CRYSTALLINE POLYESTER FOR 3D PRINTING | Genesee Valley Innovations, LLC | 2019-11-21 | — | — | US | claimed |
| US-20190352521-A1 | CURABLE UNSATURATED CRYSTALLINE POLYESTER POWDER AND METHODS OF MAKING THE SAME | Genesee Valley Innovations, LLC | 2019-11-21 | — | — | US | claimed |
| EP-3569633-A1 | COMPOSITIONS COMPRISING UNSATURATED CRYSTALLINE POLYESTER FOR 3D PRINTING | Xerox Corporation (US) | 2019-11-20 | — | — | EP | claimed |
| EP-2548900-B1 | CATIONIC NANOGELS FOR BIOTECHNOLOGICAL USES | UNIV PAIS VASCO (ES) | 2017-08-02 | — | — | EP | claimed |
| US-8940845-B2 | Method for producing water-absorbing resin | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2015-01-27 | — | — | US | claimed |
| EP-2658945-A1 | HYBRID MIXTURES FOR GAS HYDRATE INHIBITION APPLICATIONS | Akzo Nobel Chemicals International B.V. (NL) | 2013-11-06 | — | — | EP | claimed |
| WO-2012089654-A1 | HYBRID MIXTURES FOR GAS HYDRATE INHIBITION APPLICATIONS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2012-07-05 | — | — | WO | claimed |
| US-20100055592-A1 | TONER COMPOSITIONS | XEROX CORPORATION (US) | 2010-03-04 | — | — | US | claimed |
| US-12534563-B2 | Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film | ARTIENCE CO., LTD. (JP) | 2026-01-27 | — | — | US | disclosed |
| EP-0481817-A2 | Process for preparing aromatic polyester-polystyrene block copolymers | NIPPON STEEL CORPORATION (JP) | 1992-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534563-B2 | Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film | EPB41, ITGB4, ITGB5 | TOP2A 1730/4885TOP2B 945/4885ALDH1A1 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.