SCHEMBL28356552

SCHEMBL28356552

CCOC(=O)c1ccco1.O=C(O)c1ccco1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
ALDH1A1 P00352 5/20 0.54
KMT2A Q03164 5/20 0.53
MAPT P10636 4/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ABL1 P00519 1/20 0.53
F2 P00734 1/20 0.53
TSHR P16473 1/20 0.53
RIN1 Q13671 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MEN1 O00255 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
PKM P14618 1/20 0.50
KDM4E B2RXH2 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL859237 0.93 NPC1 (0.61) NPC1RAB9AALDH1A1KMT2AMAPT
Hydrochloric Acid SCHEMBL27676954 0.91 NPC1 (0.60) NPC1RAB9AALDH1A1KMT2AMAPT
SCHEMBL28204092 0.91 NPC1 (0.60) NPC1RAB9AALDH1A1KMT2AMAPT
Ethyl Acetate SCHEMBL10395121 0.87 ALDH1A1 (0.51) NPC1RAB9AALDH1A1KMT2AMAPT
Methacrylic Acid SCHEMBL20556204 0.86 NPC1 (0.52) NPC1RAB9AALDH1A1KMT2AMAPT
Ethyl Acetate SCHEMBL27960926 0.85 ALDH1A1 (0.50) NPC1RAB9AALDH1A1KMT2AMAPT
Ethoxycarbonyl Group SCHEMBL28796962 0.83 NPC1 (0.52) NPC1RAB9AALDH1A1KMT2AMAPT
SCHEMBL28882576 0.82 ALDH1A1 (0.59) NPC1RAB9AALDH1A1KMT2AMAPT
Alcohol SCHEMBL28296602 0.82 CES2 (0.56) NPC1RAB9AALDH1A1KMT2AMAPT
SCHEMBL22587545 0.81 ALDH1A1 (0.49) NPC1RAB9AALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116474826-A Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst 华南理工大学 2023-07-25 CN claimed
CN-116474826-A Preparation method and application of polyaniline-loaded palladium nanoparticle catalyst 华南理工大学 2023-07-25 CN disclosed
CN-110776668-A Environment-friendly difurancarboxylate plasticizer and application thereof 华南理工大学 2020-02-11 CN disclosed