⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283567 | 1.00 | — | — | |
| SCHEMBL1441758 | 1.00 | — | — | |
| SCHEMBL15906687 | 0.86 | L3MBTL1 (0.32) | — | |
| SCHEMBL17195640 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL17888067 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL28295821 | 0.79 | — | — | |
| SCHEMBL23283311 | 0.78 | — | — | |
| SCHEMBL20104001 | 0.78 | — | — | |
| SCHEMBL13109566 | 0.78 | — | — | |
| SCHEMBL6848021 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801989-A | Methods and compounds for the preparation of sodium-glucose cotransporter 2 inhibitors | LEXICON PHARMACEUTICALS INC | 2010-08-11 | — | — | CN | claimed |
| CN-109311861-A | Process for producing diphenylmethane derivative | 株式会社大熊制药 | 2019-02-05 | — | — | CN | disclosed |
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |
| CN-107629097-A | The solid form and its application method of a kind of compound | 莱西肯医药有限公司 | 2018-01-26 | — | — | CN | disclosed |
| US-9751876-B2 | Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension | NOVARTIS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| CN-103596564-B | diphenylmethane derivatives as SGLT2 inhibitors | GREEN CROSS CORP. (KR) | 2016-05-04 | — | — | CN | disclosed |
| US-8188135-B2 | Compounds as cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2428507-A2 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2012-03-14 | — | — | EP | disclosed |
| CN-102216277-A | Substituted benzamides as cannabinoid receptor ligands | ABBOTT LAB | 2011-10-12 | — | — | CN | disclosed |
| CN-102112483-A | Solid forms of (2S,3R,4R,5S,6R) -2- (4-chloro-3- (4-ethoxybenzyl) phenyl) -6- (methylthio) tetrahydro-2H-pyran-3, 4, 5-triol and methods of use thereof | LEXICON PHARMACEUTICALS INC | 2011-06-29 | — | — | CN | disclosed |
| EP-2334646-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2011029915-A1 | ETHER DERIVATIVES OF BICYCLIC HETEROARYLS | NOVARTIS AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| CN-101801989-A | Methods and compounds for the preparation of sodium-glucose cotransporter 2 inhibitors | LEXICON PHARMACEUTICALS INC | 2010-08-11 | — | — | CN | disclosed |
| WO-2010033543-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20100069348-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |
| US-20100069349-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |