Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | QPCT | Q16769 | 4/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602253 | 0.74 | CYP11B1 (0.53) | MAPK14BRD4GRIN2B | |
| SCHEMBL7577702 | 0.72 | CREBBP (0.40) | BRD4 | |
| SCHEMBL17067027 | 0.72 | NPC1 (0.41) | BRD4QPCTGRIN2BHDAC1 | |
| SCHEMBL28360929 | 0.69 | QPCT (0.47) | MAPK14BRD4QPCT | |
| SCHEMBL9127349 | 0.68 | GGPS1 (0.54) | PRPS1HDAC1 | |
| SCHEMBL8072413 | 0.68 | ESR1 (0.31) | — | |
| SCHEMBL15639017 | 0.68 | GRIN2B (0.49) | BRD4GRIN2B | |
| SCHEMBL28361076 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL18231503 | 0.67 | NPC1 (0.42) | HDAC1 | |
| SCHEMBL14446372 | 0.67 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |