Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935680 | 0.90 | CKS1B (0.40) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL15283620 | 0.88 | CKS1B (0.50) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL16499930 | 0.78 | CKS1B (0.42) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL7430950 | 0.77 | NQO2 (0.47) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL15189256 | 0.76 | NPC1 (0.52) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL15862041 | 0.76 | IDO1 (0.40) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL11961188 | 0.75 | CA2 (0.55) | KMT2AIDO1TDP1CA1CA2 | |
| SCHEMBL3068694 | 0.74 | SMN1; SMN2 (0.47) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL16444538 | 0.74 | SMN1; SMN2 (0.47) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL16444539 | 0.74 | SMN1; SMN2 (0.47) | CKS1BSKP1SKP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | disclosed |