Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935680 | 0.88 | CKS1B (0.40) | NQO2CKS1BSKP1SKP2TDP1 | |
| SCHEMBL15862041 | 0.85 | IDO1 (0.40) | NQO2CKS1BSKP1SKP2TDP1 | |
| SCHEMBL7430134 | 0.82 | NOX1 (0.46) | CKS1BSKP1SKP2CA12CA1 | |
| SCHEMBL17890670 | 0.80 | HTR6 (0.41) | MIFMEN1KMT2APDK1PDK2 | |
| SCHEMBL9363322 | 0.80 | TDP1 (0.49) | CKS1BSKP1SKP2TDP1CA12 | |
| SCHEMBL7430639 | 0.80 | EPHX1 (0.41) | CA12CA1CA2CA9MAPT | |
| SCHEMBL9185897 | 0.79 | TDP1 (0.45) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL15584401 | 0.79 | NQO2 (0.43) | NQO2CKS1BSKP1SKP2CA12 | |
| SCHEMBL3894800 | 0.78 | TSHR (0.42) | MIFCA12CA1CA2CA9 | |
| SCHEMBL9407493 | 0.78 | SMN1; SMN2 (0.48) | CKS1BSKP1SKP2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000048993-A1 | ARYLAMINOALKYLAMIDES | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |