SCHEMBL28357883

SCHEMBL28357883

CCOCCOCCOCCOCCOCCOCCC[Si](OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 4/20 0.32
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28428476 1.00 LMNA (0.38) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL3222134 1.00 LMNA (0.38) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL15475767 0.95 LMNA (0.38) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL718857 0.95 LMNA (0.41) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL7697341 0.91 LMNA (0.40) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL1013341 0.91 LMNA (0.39) LMNATSHRMEN1THRBHTT
SCHEMBL298549 0.88 LMNA (0.40) LMNATSHR
SCHEMBL17517381 0.87 LMNA (0.36) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL25917194 0.87 LMNA (0.36) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL16746519 0.86 LMNA (0.42) LMNAALDH1A1HPGDSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110809739-A Composition for forming silicon-containing resist underlayer film, soluble in alkaline developer 日产化学株式会社 2020-02-18 CN disclosed