Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721159 | 0.94 | LMNA (0.44) | LMNATSHR | |
| SCHEMBL28357883 | 0.91 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3222134 | 0.91 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL15475767 | 0.91 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL28428476 | 0.91 | LMNA (0.38) | LMNATSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL718857 | 0.91 | LMNA (0.41) | LMNATSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL27931302 | 0.87 | LMNA (0.42) | LMNATSHR | |
| SCHEMBL28937443 | 0.86 | LMNA (0.35) | LMNATSHR | |
| Water SCHEMBL28141773 | 0.85 | LMNA (0.41) | LMNATSHR | |
| SCHEMBL2398910 | 0.85 | LMNA (0.48) | LMNATSHRHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342097-B1 | Composition for providing an abrasion resistant coating on a substrate with a matched refractive index and controlled tintability | SDC COATINGS, INC. | 2002-01-29 | — | — | US | disclosed |