Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA3 | P07451 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL123278 | 1.00 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL8209798 | 1.00 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL8210119 | 0.97 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL5706612 | 0.97 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28296714 | 0.94 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Acetic Acid SCHEMBL6439495 | 0.91 | TSHR (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL11416580 | 0.90 | TSHR (0.86) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL1403607 | 0.90 | TSHR (0.86) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL1403625 | 0.90 | TSHR (0.86) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL175823 | 0.89 | TSHR (1.00) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957954-A | Thermoplastic resin composition for optical lens and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114451422-A | Chlorine dioxide aqueous solution based on aromatic acid and preparation method thereof | 长沙市岳麓区灵泉科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-115536538-A | Fluorine-containing diamine, fluorine-containing high-temperature-resistant nylon and preparation method thereof | 濮阳市盛通聚源新材料有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115433351-A | Optical thermoplastic resin composition and manufacturing method thereof | 万华化学集团股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114957954-A | Thermoplastic resin composition for optical lens and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114451422-A | Chlorine dioxide aqueous solution based on aromatic acid and preparation method thereof | 长沙市岳麓区灵泉科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-108034065-B | Optical polyester film and preparation method thereof | 合肥乐凯科技产业有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-111073015-A | Optical film | 合肥乐凯科技产业有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110673011-A | Semiconductor testing device | 苏州通富超威半导体有限公司 | 2020-01-10 | — | — | CN | disclosed |