Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.80 |
| ▸ | CA1 | P00915 | 3/20 | 0.75 |
| ▸ | CA2 | P00918 | 3/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | CA3 | P07451 | 1/20 | 0.75 |
| ▸ | TYR | P14679 | 1/20 | 0.75 |
| ▸ | DRD1 | P21728 | 1/20 | 0.75 |
| ▸ | CA4 | P22748 | 1/20 | 0.75 |
| ▸ | CA6 | P23280 | 1/20 | 0.75 |
| ▸ | CA5A | P35218 | 1/20 | 0.75 |
| ▸ | CA7 | P43166 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.75 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.73 |
| ▸ | DAO | P14920 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5053781 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 1.00 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1065024 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6664065 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10823257 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9484769 | 0.96 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112048071-B | Preparation method and application of MOF material with adjustable proton conduction performance | 曲阜师范大学 | 2022-07-01 | — | — | CN | claimed |
| CN-112074974-A | Particulate silicon-containing active material, negative electrode, lithium ion battery cell, transportation vehicle, and methods of manufacturing active material and electrode | 大众汽车股份公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112048071-A | Preparation method and application of MOF material with adjustable proton conduction performance | 曲阜师范大学 | 2020-12-08 | — | — | CN | claimed |
| CN-108701598-A | Base film for semiconductor processing sheet and semiconductor processing sheet | 琳得科株式会社 | 2018-10-23 | — | — | CN | claimed |
| CN-105820468-A | Durable plastic cloth | 界首市锦丰塑业有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-105801977-A | Anti-aging plastic cloth | 界首市锦丰塑业有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-103703137-A | Method for producing useful chemicals from potassium terephthalate | GENARIS INC | 2014-04-02 | — | — | CN | claimed |
| US-20110120464-A1 | INHALERS | INNOVATA BIOMED LIMITED (GB) | 2011-05-26 | — | — | US | claimed |
| US-20240261759-A1 | Method Of Manufacture Of UiO-66 Having Specific Micropore Volume | ExxonMobil Technology and Engineering Company | 2024-08-08 | — | — | US | disclosed |
| CN-117154084-B | Negative plate and lithium ion battery | 荣耀终端有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-20240139722-A1 | ORGANO-PHOSPHATE MODIFIED METAL ORGANIC FRAMEWORKS AND APPLICATIONS | THE JOHNS HOPKINS UNIVERSTY | 2024-05-02 | — | — | US | disclosed |
| EP-4347608-A1 | METHOD OF MANUFACTURE OF UIO-66 HAVING SPECIFIC MICROPORE VOLUME | ExxonMobil Technology and Engineering Company (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2024045639-A1 | METHOD FOR PREPARING PENT COPOLYESTER | 科泽新材料股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| CN-112074974-B | Particulate silicon-containing active material, negative electrode, lithium ion battery cell, transportation vehicle, and method of making active material and electrode | 大众汽车股份公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-1992008608-A1 | BALLISTIC RESISTANT FABRIC ARTICLES | ALLIED-SIGNAL INC. (US) | 1992-05-29 | — | — | WO | disclosed |
| US-5116670-A | Composed of polybasic acid and polyhydric alcohol; ester bonded to one terminal; electronics | SHOWA DENKO K.K. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5008450-A | Multi-stage separation from aliphatic carboxylic acid | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4931538-A | Copolyester and polyester resin composition comprising said copolyester | KURARAY CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4475330-A | COPOLYMERS OR BLEND OF ETHYLENE, TRIMETHYLENE, AND/OR TETRAMETHYLENE TEREPHTHALATE | TEIJIN LIMITED (JP) | 1984-10-09 | — | — | US | disclosed |
| US-4268410-A | Polyether polyester surfactants, their production and uses | HONEYWILL-ATLAS LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |