Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358559 | 0.87 | PTGS2 (0.68) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11250330 | 0.86 | POLB (1.00) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30511886 | 0.85 | POLB (0.97) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28358360 | 0.84 | PTGS2 (0.94) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3447906 | 0.84 | PTGS2 (1.00) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5820153 | 0.83 | POLB (0.73) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23928527 | 0.81 | PTGS2 (0.80) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11243639 | 0.81 | POLB (0.89) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11254624 | 0.81 | PTGS2 (0.80) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23392558 | 0.81 | PTGS2 (0.86) | POLBPTGS2KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746355-B | Phenylpyrazole compound, pharmaceutical composition, and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-08-11 | — | — | CN | disclosed |
| CN-110746355-A | Phenylpyrazole compound, pharmaceutical composition, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-02-04 | — | — | CN | disclosed |