SCHEMBL28358586

SCHEMBL28358586

CC(C1CCCCCC1)C1CCCCNC1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
CCR2 P41597 7/20 0.38
MMP1 P03956 5/20 0.36
MMP3 P08254 2/20 0.36
MMP2 P08253 1/20 0.36
MMP7 P09237 1/20 0.36
MMP8 P22894 1/20 0.36
PSEN1 P49768 2/20 0.34
PSEN2 P49810 2/20 0.34
APH1B Q8WW43 2/20 0.34
NCSTN Q92542 2/20 0.34
APH1A Q96BI3 2/20 0.34
PSENEN Q9NZ42 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CTSD P07339 1/20 0.34
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3397946 0.81 CCR2 (0.41) HTTCCR2MMP1MMP3MMP2
SCHEMBL12875886 0.81 CCR2 (0.41) HTTCCR2MMP1MMP3MMP2
SCHEMBL28354951 0.81 HTT (0.38) HTTCCR2MMP1MMP3MMP2
SCHEMBL7624107 0.75 HTT (0.42) HTTCCR2MMP1MMP3MMP2
SCHEMBL10160076 0.75 L3MBTL1 (0.43) HTTCCR2MMP1MMP3L3MBTL1
SCHEMBL6734281 0.75 L3MBTL1 (0.43) HTTCCR2MMP1MMP3L3MBTL1
SCHEMBL12210573 0.75 L3MBTL1 (0.43) HTTCCR2MMP1MMP3L3MBTL1
SCHEMBL3816676 0.73 CCR2 (0.36) HTTCCR2MMP1MMP3L3MBTL1
SCHEMBL13012659 0.72 KMT2A (0.42) KDM4E
SCHEMBL13012660 0.72 KMT2A (0.47) HTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110787300-B Composition containing sodium hyaluronate and preparation and application thereof 中山万远新药研发有限公司 2020-09-22 CN claimed
CN-110787300-B Composition containing sodium hyaluronate and preparation and application thereof 中山万远新药研发有限公司 2020-09-22 CN disclosed
CN-110787300-A Composition containing sodium hyaluronate and preparation and application thereof 中山万远新药研发有限公司 2020-02-14 CN disclosed