SCHEMBL283587

SCHEMBL283587

O=C(O)Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.71
KDM4E B2RXH2 3/20 0.58
TSHR P16473 3/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
RGS12 O14924 1/20 0.55
LMNA P02545 1/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55
NFKB1 P19838 1/20 0.55
APEX1 P27695 1/20 0.55
THPO P40225 1/20 0.55
BLM P54132 1/20 0.55
GNAI1 P63096 1/20 0.55
PMP22 Q01453 1/20 0.55
HIF1A Q16665 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PIK3CA P42336 1/20 0.54
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL7951771 0.98 CA2 (0.69) CA2KDM4ETSHRMAPTHPGD
Hydrochloric Acid SCHEMBL2530252 0.98 CA2 (0.69) CA2KDM4ETSHRMAPTHPGD
Methyl Alcohol SCHEMBL7045180 0.96 CA2 (0.67) CA2KDM4ETSHRMAPTHPGD
SCHEMBL11361475 0.88 HAO1 (0.58) CA2KDM4ETSHRMAPTHPGD
SCHEMBL377506 0.83 CA2 (1.00) CA2KDM4ETSHRMAPTHPGD
SCHEMBL11859884 0.83 CA2 (0.67) CA2KDM4ETSHRMAPTHPGD
SCHEMBL585295 0.83 CA2 (0.72) CA2KDM4ETSHRMAPTHPGD
SCHEMBL2164422 0.83 HAO1 (0.57) CA2KDM4ETSHRBLMPIK3CA
SCHEMBL659220 0.83 PIK3CA (0.54) CA2TSHRPIK3CAKMT2AIDO1
SCHEMBL1245996 0.82 CA2 (0.59) CA2KDM4ETSHRMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283659-B Preparation method and application of m-nitrobenzonitrile 上海忝晴化工有限公司 2025-04-25 CN claimed
CN-114994196-B High performance liquid chromatography separation method for guanfacine hydrochloride intermediate 2, 6-dichlorophenylacetic acid and impurities 上海应用技术大学 2024-12-31 CN claimed
CN-114671781-B Method for converting arylbenzylamine into arylnitrile compound 南通大学 2024-04-19 CN claimed
CN-116283659-A Preparation method and application of m-nitrobenzonitrile 上海忝晴化工有限公司 2023-06-23 CN claimed
CN-112063005-B Preparation method of molecular imprinting integral needle type extraction device for enriching polychlorinated biphenyl 吉林化工学院 2022-12-06 CN claimed
CN-114671781-A Method for efficiently converting arylbenzylamine into aryl nitrile compound 南通大学 2022-06-28 CN claimed
CN-114478122-A Novel functional fertilizer synergist and application 郑州郑氏化工产品有限公司 2022-05-13 CN claimed
CN-109535080-B Synthesis method of benzimidazole derivative 广东省石油与精细化工研究院 2021-01-01 CN claimed
CN-112063005-A Preparation method of molecular imprinting integral needle type extraction device for enriching polychlorinated biphenyl 吉林化工学院 2020-12-11 CN claimed
EP-3097084-B1 NEW KALLIKREIN 7 INHIBITORS SIXERA PHARMA AB (SE) 2020-09-30 EP claimed
EP-2411375-A1 PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5 TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION Poxel (FR) 2012-02-01 EP claimed
WO-2010109015-A1 PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5 TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION POXEL (FR) 2010-09-30 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 CA2 32/4885KDM4E 1814/4885TSHR 2894/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 CA2 664/4885KDM4E 1567/4885TSHR 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.