SCHEMBL221408

SCHEMBL221408

C=CC(=O)OC(F)(F)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 5/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5277731 0.93 ALDH1A1 (0.32) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL786625 0.86 ALDH1A1 (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL21819966 0.85 ALDH1A1 (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL8667601 0.84
SCHEMBL11530545 0.84
SCHEMBL8520685 0.84
SCHEMBL786417 0.82 ALDH1A1 (0.33) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL10770317 0.82 ALDH1A1 (0.33) ALDH1A1TP53HIF1ACYP3A4MAPK1
Acrylic Acid SCHEMBL29143629 0.80 LMNA (0.43) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL757673 0.80 THRB (0.33) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452193-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
CN-118382418-A Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer 欧莱雅 2024-07-23 CN disclosed
EP-3435962-B1 DEVICE FOR APPLYING A COMPOSITION IN THE FORM OF AN EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS OREAL (FR) 2024-05-22 EP disclosed
EP-3435963-B1 EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS AND COSMETIC PROCESS OREAL (FR) 2024-05-01 EP disclosed
CN-111183398-B Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus 三菱化学株式会社 2023-09-22 CN disclosed
WO-2023118530-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2023-06-29 WO disclosed
US-11547196-B2 Device for applying a composition in the form of an emulsion comprising a film-forming agent and non-volatile oils L'OREAL (FR) 2023-01-10 US disclosed
US-11497705-B2 Anhydrous liquid composition comprising oils, a film-forming polymer, a monoalcohol and a particulate material L'OREAL (FR) 2022-11-15 US disclosed
US-11482706-B2 Resin for energy device electrode, composition for forming energy device electrode, energy device electrode, and energy device SHOWA DENKO MATERIALS CO., LTD. (JP) 2022-10-25 US disclosed
CN-114678597-A Lithium ion battery 日立化成株式会社 2022-06-28 CN disclosed
US-5814567-A POLYSACCHARIDE COATING FOR DISPOSABLE ABSORBENT PRODUCTS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-09-29 US disclosed
US-5733603-A VINYL POLYMER FOR SURFACE ACTIVE AGENTS, DISSOLVING AND IMMERSION TO COAT A SUBSTRATE, RINSING AFTER REMOVAL FROM SOLUTIONS KIMBERLY-CLARK CORPORATION (US) 1998-03-31 US disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997047801-A1 DURABLE HYDROPHILIC COATING FOR A POROUS HYDROPHOBIC POLYMER SUBSTRATE KIMBERLY-CLARK WORLDWIDE, INC. (US) 1997-12-18 WO disclosed
EP-0507204-B1 Liquid crystal device, display apparatus using same and display method using same CANON KK (JP) 1996-11-20 EP disclosed
US-5268783-A Liquid crystal device including a polymer having a surface energy of at most 25 dyn/cm, display apparatus using same and display method using same CANON KABUSHIKI KAISHA (JP) 1993-12-07 US disclosed
EP-0303036-B1 ELECTRICALLY SUPERCONDUCTING METAL-CERAMIC COATINGS International Business Machines Corporation (US) 1993-05-19 EP disclosed
EP-0507204-A1 Liquid crystal device, display apparatus using same and display method using same CANON KABUSHIKI KAISHA (JP) 1992-10-07 EP disclosed
US-4981840-A FLUOROPOLYMER, SOLVENT INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-01-01 US disclosed
EP-0303036-A2 Electrically superconducting metal-ceramic coatings International Business Machines Corporation (US) 1989-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11547196-B2 Device for applying a composition in the form of an emulsion comprising a film-forming agent and non-volatile oils DAGLA, NONO, LIPA ALDH1A1 2692/4885TP53 659/4885HIF1A 2110/4885
US-11497705-B2 Anhydrous liquid composition comprising oils, a film-forming polymer, a monoalcohol and a particulate material KRT18, VIM, DSG1 ALDH1A1 2639/4885TP53 2293/4885HIF1A 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.