Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985062 | 0.83 | ALDH1A1 (0.44) | GAAMAPK1ERN1MEN1KMT2A | |
| SCHEMBL28549978 | 0.81 | AR (0.38) | GAAMAPK1RXFP1ERN1MEN1 | |
| SCHEMBL31248747 | 0.80 | AR (0.38) | GAAMAPK1RXFP1ERN1MEN1 | |
| SCHEMBL28362640 | 0.79 | VCAM1 (0.42) | MAPK1RXFP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL220261 | 0.79 | PDGFRB (0.38) | MEN1KMT2AARPGRCYP3A4 | |
| SCHEMBL28362551 | 0.77 | VCAM1 (0.46) | MAPK1MEN1KMT2APGRCYP3A4 | |
| SCHEMBL31312674 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2 | |
| SCHEMBL28362598 | 0.76 | MAPK1 (0.37) | GAAMAPK1RXFP1ERN1AR | |
| SCHEMBL7784821 | 0.76 | HRAS (0.41) | GAAMAPK1RXFP1MEN1KMT2A | |
| SCHEMBL10322564 | 0.75 | ALDH1A1 (0.38) | MAPK1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248472-B | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113248472-A | Anti-osteoporosis compound and derivative thereof, pharmaceutical composition, preparation method and application | 中国药科大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-110818609-A | Preparation method and application of 3-acetyl indole BRPF1 inhibitor | 中国药科大学 | 2020-02-21 | — | — | CN | disclosed |