SCHEMBL28359062

SCHEMBL28359062

NC(=O)CC(=O)Nc1ccc2ncccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.72
CYP3A4 P08684 2/20 0.72
CYP1A2 P05177 1/20 0.72
TSHR P16473 1/20 0.72
HSD17B10 Q99714 1/20 0.72
NPC1 O15118 7/20 0.68
POLB P06746 2/20 0.68
MEN1 O00255 1/20 0.68
MAPT P10636 1/20 0.68
KMT2A Q03164 1/20 0.68
PABPC1 P11940 1/20 0.60
NOTUM Q6P988 2/20 0.60
HDAC6 Q9UBN7 2/20 0.59
HDAC1 Q13547 2/20 0.57
HDAC3 O15379 1/20 0.57
HDAC4 P56524 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC2 Q92769 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29944526 0.91 NPC1 (0.77) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL5142389 0.91 NPC1 (0.77) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL4960580 0.85 NPC1 (0.77) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL8402849 0.84 NPC1 (0.70) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL2638441 0.84 NPC1 (0.70) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL27599014 0.84 NPC1 (0.70) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL2638443 0.84 HDAC6 (0.72) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL4858749 0.84 NPC1 (0.70) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL21296585 0.84 NPC1 (0.70) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10
SCHEMBL6115640 0.84 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP1A2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642784-B Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2022-09-20 CN claimed
CN-110642784-A Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2020-01-03 CN claimed
CN-110642784-B Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2022-09-20 CN disclosed
CN-110642784-B Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2022-09-20 CN disclosed
CN-110642784-A Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2020-01-03 CN disclosed
CN-110642784-A Quinoline bis-quaternary ammonium salt type pickling corrosion inhibitor and preparation method thereof 山西大学 2020-01-03 CN disclosed