Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922622 | 1.00 | SYK (0.43) | SYKMEN1KMT2AUSP2PABPC1 | |
| SCHEMBL29552428 | 1.00 | SYK (0.43) | SYKMEN1KMT2AUSP2PABPC1 | |
| SCHEMBL29551786 | 0.88 | SYK (0.44) | SYKMEN1KMT2AUSP2PABPC1 | |
| SCHEMBL29922724 | 0.83 | SYK (0.46) | SYKMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL28359017 | 0.83 | SYK (0.46) | SYKMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL29552340 | 0.80 | DHODH (0.45) | KMT2AL3MBTL1MAPTALDH1A1DHODH | |
| SCHEMBL28362738 | 0.80 | DHODH (0.45) | KMT2AL3MBTL1MAPTALDH1A1DHODH | |
| SCHEMBL29922784 | 0.80 | DHODH (0.45) | KMT2AL3MBTL1MAPTALDH1A1DHODH | |
| SCHEMBL15091096 | 0.79 | SYK (0.56) | SYKMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL28359212 | 0.79 | SYK (0.40) | SYKMEN1KMT2AUSP2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110818641-A | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2020-02-21 | — | — | CN | disclosed |