Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.63 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29884015 | 0.84 | ADORA2B (0.67) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL11213748 | 0.84 | ADORA2B (0.58) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL23974961 | 0.83 | ADORA2B (0.65) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL9295135 | 0.79 | ADORA2B (0.52) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8072026 | 0.78 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8952269 | 0.78 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8076046 | 0.78 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| Caffeine SCHEMBL8569482 | 0.78 | ADORA2B (1.00) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| Caffeine SCHEMBL901194 | 0.78 | ADORA2B (1.00) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| Caffeine SCHEMBL29549294 | 0.78 | ADORA2B (1.00) | ADORA2BADORA2AACHEPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831972-A | anti-PD-L1 antibodies and methods of making and using the same | 西雅图免疫公司 | 2020-02-21 | — | — | CN | disclosed |