SCHEMBL28359797

SCHEMBL28359797

O=C(Cc1c[nH]c2ccccc12)NC(CS)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 7/20 0.62
ACE P12821 4/20 0.61
P2RY14 Q15391 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28359796 1.00 ECE1 (0.62) ECE1ACEP2RY14
SCHEMBL6138173 0.88 P2RY14 (0.56) ECE1ACEP2RY14
SCHEMBL3728145 0.88 ALOX15 (0.70) ACEP2RY14
SCHEMBL13278205 0.88 ALOX15 (0.70) ACEP2RY14
SCHEMBL29987387 0.88 ALOX15 (0.70) ACEP2RY14
SCHEMBL28359800 0.88 ALDH1A1 (0.61) ECE1ACE
SCHEMBL28359802 0.88 ALDH1A1 (0.61) ECE1ACE
SCHEMBL468341 0.87 ACE (0.57) ECE1ACEP2RY14
SCHEMBL149555 0.87 ACE (0.57) ECE1ACEP2RY14
SCHEMBL29986695 0.87 ACE (0.57) ECE1ACEP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693659-A Two-step mixed mode chromatography method for separating recombinant human serum albumin 浙江大学 2023-09-05 CN claimed
CN-110681362-B Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-09-11 CN claimed
CN-110681362-A Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-01-14 CN claimed
CN-116693659-A Two-step mixed mode chromatography method for separating recombinant human serum albumin 浙江大学 2023-09-05 CN disclosed
CN-116693659-A Two-step mixed mode chromatography method for separating recombinant human serum albumin 浙江大学 2023-09-05 CN disclosed
CN-110681362-B Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-09-11 CN disclosed
CN-110681362-B Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-09-11 CN disclosed
CN-110681362-A Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-01-14 CN disclosed
CN-110681362-A Mixed-mode chromatography medium with carboxyl and indolyl as functional groups 浙江大学 2020-01-14 CN disclosed