Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.36 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.35 |
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.35 |
| ▸ | SCN4A known ✓ | P35499 | 1/20 | 0.35 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970570 | 0.91 | BACE1 (0.43) | BACE1DDB1CRBNOPRM1OPRL1 | |
| SCHEMBL22438572 | 0.72 | BACE1 (0.41) | BACE1DDB1CRBNCACNA1FALDH1A1 | |
| SCHEMBL34464661 | 0.69 | DDB1 (0.40) | BACE1DDB1CRBNCACNA1FALDH1A1 | |
| SCHEMBL21157864 | 0.69 | LMNA (0.50) | BACE1ALDH1A1MAPTKCNH2MEN1 | |
| SCHEMBL1568276 | 0.68 | CYP19A1 (0.68) | BACE1DDB1CRBNOPRM1OPRL1 | |
| SCHEMBL38654772 | 0.68 | BACE1 (0.45) | BACE1DDB1CRBNCACNA1FALDH1A1 | |
| SCHEMBL15657386 | 0.67 | CFTR (0.45) | BACE1OPRM1OPRL1CACNA1FALDH1A1 | |
| SCHEMBL10834099 | 0.67 | PDK2 (0.50) | BACE1ALDH1A1MAPTKCNH2MEN1 | |
| SCHEMBL2308362 | 0.66 | GRIN1 (0.51) | BACE1OPRM1OPRL1CACNA1FALDH1A1 | |
| Phenytoin SCHEMBL27471325 | 0.66 | CYP2C9 (0.81) | CACNA1FALDH1A1MAPTCYP2C9HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110680959-B | Hydrogel for repairing multiple cross-linked meniscus and preparation method thereof | 江苏地韵医疗科技有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-110680959-A | Hydrogel for repairing multiple cross-linked meniscus and preparation method thereof | 江苏地韵医疗科技有限公司 | 2020-01-14 | — | — | CN | disclosed |