Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29218953 | 1.00 | SLC22A1 (0.58) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL4543349 | 0.97 | SLC22A1 (0.61) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL15912723 | 0.97 | SLC22A1 (0.61) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL28755201 | 0.97 | SLC22A1 (0.61) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL721018 | 0.95 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4895225 | 0.95 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4893513 | 0.95 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL9575880 | 0.95 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL491727 | 0.95 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL28193107 | 0.94 | SLC22A1 (0.58) | SLC22A1DNM1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119331405-A | Low-stress PC/ABS alloy | 南京金杉汽车工程塑料有限责任公司 | 2025-01-21 | — | — | CN | claimed |
| CN-111471328-B | Modification method of hydrotalcite powder and application of hydrotalcite powder in calcium-zinc stabilizer | 杭州临安华立塑胶有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-111471328-A | Modification method of hydrotalcite powder and application of hydrotalcite powder in calcium-zinc stabilizer | 杭州临安华立塑胶有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111333915-A | Novel calcium-zinc stabilizer for PVC-U plate and preparation method thereof | 杭州临安华立塑胶有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-110835111-A | Preparation process of bentonite for oil-based drilling fluid | 浙江树人学院（浙江树人大学） | 2020-02-25 | — | — | CN | claimed |
| CN-119331405-A | Low-stress PC/ABS alloy | 南京金杉汽车工程塑料有限责任公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-111471328-B | Modification method of hydrotalcite powder and application of hydrotalcite powder in calcium-zinc stabilizer | 杭州临安华立塑胶有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-110835111-B | Preparation process of bentonite for oil-based drilling fluid | 浙江树人学院（浙江树人大学） | 2021-07-09 | — | — | CN | disclosed |
| CN-111471328-A | Modification method of hydrotalcite powder and application of hydrotalcite powder in calcium-zinc stabilizer | 杭州临安华立塑胶有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-111333915-A | Novel calcium-zinc stabilizer for PVC-U plate and preparation method thereof | 杭州临安华立塑胶有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-110835111-A | Preparation process of bentonite for oil-based drilling fluid | 浙江树人学院（浙江树人大学） | 2020-02-25 | — | — | CN | disclosed |