Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL491727 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL721018 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4893513 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4895225 | 1.00 | SLC22A1 (0.52) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL11466080 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL15973366 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7702551 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL2839296 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL2858689 | 0.95 | ALDH1A1 (0.57) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL11127927 | 0.95 | ALDH1A1 (0.57) | SLC22A1DNM1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371406-B1 | OXYALKYLATED QUATERNARY AMMONIUM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID COMPOUNDS | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5076828-A | Immersing seeds into quaternary solution prior to planting | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |