Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504853 | 0.79 | HDAC6 (0.49) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL4582422 | 0.79 | TDP1 (0.54) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL18294910 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL21943233 | 0.75 | HDAC6 (0.51) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL6879552 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ETSHRHDAC6 | |
| SCHEMBL16675141 | 0.74 | HDAC6 (0.44) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL4399532 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL16483989 | 0.71 | ALDH1A1 (0.47) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL183387 | 0.71 | MAPT (0.70) | MAPTALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL18294907 | 0.71 | HDAC6 (0.51) | MAPTALDH1A1TDP1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141123-B | Compound, preparation method thereof and application thereof in preparation of dual inhibitors of histone deacetylase and epoxide hydrolase | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-115141123-A | Compound, preparation method thereof and application thereof in preparation of histone deacetylase and epoxide hydrolase dual inhibitor | 沈阳药科大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-110835406-B | Free radical monomer containing diphenylamine structure and preparation method and application of polymer thereof | 武汉理工大学 | 2020-09-01 | — | — | CN | disclosed |
| CN-110835406-A | Novel free radical monomer containing diphenylamine structure and preparation method and application of polymer thereof | 武汉理工大学 | 2020-02-25 | — | — | CN | disclosed |