SCHEMBL183387

SCHEMBL183387

Nc1nc(N)nc(N(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
TSHR P16473 4/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
LMNA P02545 2/20 0.68
NPC1 O15118 1/20 0.68
JAK2 O60674 1/20 0.68
RAB9A P51151 1/20 0.68
PKM P14618 1/20 0.58
ALDH1A1 P00352 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
PRNP P04156 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683721 0.92 MAPT (0.62) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL17799137 0.92 MAPT (0.62) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL3502325 0.86 ALDH1A1 (0.75) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL77495 0.83 ALDH1A1 (0.70) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL13363710 0.82 MAPT (1.00) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL12134585 0.82 NPC1 (1.00) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL31528560 0.80 MAPT (0.54) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL581128 0.80 MAPT (0.54) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL3500555 0.80 ALDH1A1 (0.66) MAPTTSHRSMN1; SMN2LMNANPC1
SCHEMBL14869412 0.78 DHFR (0.54) MAPTTSHRSMN1; SMN2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685933-B Polyformaldehyde composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-01-02 CN claimed
CN-114685933-A Polyformaldehyde composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2022-07-01 CN claimed
EP-1608339-B8 PHARMACEUTICAL CO-CRYSTAL OF CELECOXIB-NICOTINAMIDE MCNEIL PPC INC (US) 2012-04-25 EP claimed
EP-1631260-A2 PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS OF DRUGS SUCH AS CARBAMAZEPINE, CELECOXIB, OLANZAPINE, ITRACONAZOLE, TOPIRAMATE, MODAFINIL, 5-FLUOROURACIL, HYDROCHLOROTHAZIDE, ACETAMINOPHEN, ASPIRIN, FLURBIPROFEN, PHENYTOIN AND IBUPROFEN Transform Pharmaceuticals, Inc. (US) 2006-03-08 EP claimed
EP-1608339-A1 PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS OF DRUGS SUCH AS CARBAMAZEPINE, CELECOXIB, OLANZAPINE, ITRACONAZOLE, TOPIRAMATE, MODAFINIL, 5-FLUOROURACIL, HYDROCHLOROTHIAZIDE, ACETAMINOPHEN, ASPIRIN, FLURBIPROFEN, PHENYTOIN AND IBUPROFEN Transform Pharmaceuticals, Inc. (US) 2005-12-28 EP claimed
WO-2004078161-A1 PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS OF DRUGS SUCH AS CARBAMAZEPTINE, CELECOXIB, OLANZAPINE, ITRACONAZOLE, TOPIRAMATE, MODAFINIL, 5-FLUOROURACIL, HYDROCHLOROTHIAZIDE, ACETAMINOPHEN, ASPIRIN, FLURBIPROFEN, PHENYTOIN AND IBUPROFEN TRANSFORM PHARMACEUTICALS, INC. (US) 2004-09-16 WO claimed
WO-2004078163-A2 PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS OF DRUGS SUCH AS CARBAMAZEPINE, CELECOXIB, OLANZAPINE, ITRACONAZOLE, TOPIRAMATE, MODAFINIL, 5-FLUOROURACIL, HYDROCHLOROTHIAZIDE, ACETAMINOPHEN, ASPIRIN, FLURBIPROFEN, PHENYTOIN AND IBUPROFEN TRANSFORM PHARMACEUTICALS, INC. (US) 2004-09-16 WO claimed
US-6384179-B1 None US disclosed
US-20250360691-A1 RELEASE FILM AND LAMINATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-11-27 US disclosed
US-20250333609-A1 HYDROPHILIC COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-30 US disclosed
US-20250312846-A1 GREEN MOLDED BODY, SINTERED MOLDED BODY, AND MANUFACTURING METHOD FOR THE SAME ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-10-09 US disclosed
EP-3431520-B1 PROCESS FOR PRODUCING OXYMETHYLENE COPOLYMER MITSUBISHI GAS CHEMICAL CO (JP) 2025-09-24 EP disclosed
CN-118878801-B Phosphorus-nitrogen synergistic structure type flame-retardant PET and preparation method thereof 福建师范大学泉港石化研究院 2025-09-12 CN disclosed
EP-0289142-A2 Polyacetal molding compositions HOECHST CELANESE CORPORATION (US) 1988-11-02 EP disclosed
US-4751272-A POLYMERIZING TRIOXANE AND CYCLIC ETHER; BORON TRIFLUORIDE CATALYST TORAY INDUSTRIES, INC. (JP) 1988-06-14 US disclosed
EP-0270279-A1 Polyacetal stabilizer formulation with improved color stability HOECHST CELANESE CORPORATION (US) 1988-06-08 EP disclosed
US-4731396-A Thermal stabilization of acetal polymers CELANESE CORPORATION (US) 1988-03-15 US disclosed
EP-0244245-A2 Process for producing oxymethylene copolymer and resinous composition TORAY INDUSTRIES, INC. (JP) 1987-11-04 EP disclosed
EP-0235927-A2 Stabilized oxymethylene polymers CELANESE CORPORATION (US) 1987-09-09 EP disclosed
US-4342680-A WITH AN AMINE SUBSTITUTED TRIAZINE, A PHENOL, AND AN ALKALI METAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-08-03 US disclosed