Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340223 | 0.88 | SLC6A2 (0.51) | TTRSLC6A2SLC6A3HPGDMAPT | |
| SCHEMBL4965689 | 0.88 | TTR (0.58) | TTRSLC6A2SLC6A3HPGDMAPT | |
| SCHEMBL28364234 | 0.81 | CYP1A2 (0.46) | TTRSLC6A2SLC6A3MAPTLMNA | |
| SCHEMBL641111 | 0.81 | CYP2C9 (0.56) | TTRSLC6A2SLC6A3HPGDMAPT | |
| Hydrochloric Acid SCHEMBL2884722 | 0.79 | CYP2C9 (0.54) | TTRSLC6A2SLC6A3HPGDMAPT | |
| SCHEMBL3045884 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A3MAPTALDH1A1GAA | |
| SCHEMBL3652668 | 0.78 | MAPT (0.63) | TTRSLC6A2SLC6A3HPGDMAPT | |
| SCHEMBL2395063 | 0.78 | PTGS2 (0.44) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3049386 | 0.78 | ALDH1A1 (0.54) | TTRSLC6A2SLC6A3HPGDMAPT | |
| SCHEMBL7186092 | 0.78 | TTR (0.75) | TTRSLC6A2SLC6A3HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336380-B | Pyrazole amide compound containing diphenyl ether structure, preparation method and application thereof | 浙江省化工研究院有限公司 | 2020-03-17 | — | — | CN | disclosed |