SCHEMBL28360604

SCHEMBL28360604

CCCCCCOc1cc(OC)c(C=O)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
PLA2G2A P14555 2/20 0.47
ERN1 O75460 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
PLA2G4B P0C869 1/20 0.43
BLM P54132 1/20 0.42
SMPD1 P17405 3/20 0.42
MAOB P27338 2/20 0.41
NR5A1 Q13285 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12223477 0.93 LMNA (0.50) LMNAERN1THRATHRBMAOB
SCHEMBL308232 0.90 PLA2G2A (0.50) PLA2G2ATHRATHRBPLA2G4BBLM
SCHEMBL309333 0.90 PLA2G2A (0.50) PLA2G2ATHRATHRBPLA2G4BBLM
SCHEMBL307515 0.90 PLA2G2A (0.50) PLA2G2ATHRATHRBPLA2G4BBLM
SCHEMBL306743 0.90 PLA2G2A (0.50) PLA2G2ATHRATHRBPLA2G4BBLM
SCHEMBL308364 0.90 PLA2G2A (0.50) PLA2G2ATHRATHRBPLA2G4BBLM
SCHEMBL28356840 0.90 ERN1 (0.63) LMNAPLA2G2AERN1THRATHRB
SCHEMBL23932615 0.84 ERN1 (0.46) LMNAERN1MAOB
SCHEMBL3547233 0.82 ERN1 (0.47) LMNAERN1MAOB
SCHEMBL23932614 0.81 ERN1 (0.44) LMNAERN1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110845345-B Aromatic diamine monomer and preparation method thereof 中国科学院长春应用化学研究所 2021-11-09 CN disclosed
CN-110791833-B Polyimide fiber and preparation method thereof 中国科学院长春应用化学研究所 2021-02-05 CN disclosed
CN-110845345-A Aromatic diamine monomer and preparation method thereof 中国科学院长春应用化学研究所 2020-02-28 CN disclosed
CN-110791833-A Polyimide fiber and preparation method thereof 中国科学院长春应用化学研究所 2020-02-14 CN disclosed