Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701092 | 0.85 | GSR (0.44) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL10996556 | 0.75 | LMNA (0.52) | LMNAMAPK1SRCCYP2D6HPGD | |
| SCHEMBL28852021 | 0.73 | GSR (0.42) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL6568664 | 0.73 | GSR (0.42) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL15811785 | 0.73 | GSR (0.42) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL5526317 | 0.73 | GSR (0.42) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL3701094 | 0.72 | GSR (0.44) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL74691 | 0.71 | SRC (0.48) | LMNAMAPK1SRCCYP2D6GSR | |
| SCHEMBL156309 | 0.70 | GSR (0.46) | LMNAMAPK1SRCCYP2D6GSR | |
| Benzene SCHEMBL27929647 | 0.70 | GSR (0.46) | LMNAMAPK1SRCCYP2D6GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840847-A | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2020-02-28 | — | — | CN | disclosed |