Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360704 | 0.85 | LMNA (0.44) | GSRLMNAKMT2ASRCCYP2D6 | |
| SCHEMBL6568664 | 0.83 | GSR (0.42) | GSRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL28852021 | 0.83 | GSR (0.42) | GSRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL15811785 | 0.83 | GSR (0.42) | GSRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5526317 | 0.83 | GSR (0.42) | GSRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL3701094 | 0.81 | GSR (0.44) | GSRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL407211 | 0.78 | GSR (0.42) | GSRLMNAALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL4917874 | 0.77 | MAPK1 (0.47) | GSRKDM4EMAPTNPSR1TDP1 | |
| SCHEMBL156309 | 0.74 | GSR (0.46) | GSRLMNAALDH1A1KMT2ASRC | |
| Benzene SCHEMBL27929647 | 0.74 | GSR (0.46) | GSRLMNAALDH1A1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-104109235-B | A kind of single functionalized poly (ethylene glycol), preparation method and its bio-related substance with nitrogen-atoms branch centers | 厦门赛诺邦格生物科技股份有限公司 | 2017-07-18 | — | — | CN | claimed |
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | disclosed |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-01-30 | — | — | US | disclosed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | disclosed |
| WO-2003053845-A2 | CHEMICAL FUNCTIONALIZATION NANOLITHOGRAPHY | PENN STATE RESEARCH FOUNDATION (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-0185762-B1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0185762-A4 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-12-01 | — | — | EP | disclosed |
| US-4625014-A | Cell-delivery agent | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0185762-A1 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000527-A1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | GSR 1539/4885LMNA 4134/4885ALDH1A1 4557/4885 |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | PHOSPHO1, PLCB3, INPP5D | GSR 1486/4885LMNA 3315/4885ALDH1A1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.