Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360765 | 0.85 | KDM4E (0.45) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL28561809 | 0.80 | KDM4E (0.49) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL30242148 | 0.79 | KDM4E (0.48) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL28980152 | 0.79 | KDM4E (0.48) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL523339 | 0.79 | KDM4E (0.56) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL522736 | 0.78 | MAPT (0.55) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL28883876 | 0.75 | LMNA (0.41) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL29156670 | 0.73 | KMT2A (0.45) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL29156701 | 0.73 | KMT2A (0.50) | KMT2ALMNASMN1; SMN2MEN1KDM4E | |
| SCHEMBL30744814 | 0.73 | KMT2A (0.50) | KMT2ALMNASMN1; SMN2MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543081-B | Preparation method of 1-difluoroalkylisoquinoline | 四川理工学院 | 2020-02-18 | — | — | CN | disclosed |