Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360747 | 0.85 | KMT2A (0.48) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL28980152 | 0.80 | KDM4E (0.48) | KDM4EKMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30242148 | 0.80 | KDM4E (0.48) | KDM4EKMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28080770 | 0.73 | ACSS2 (0.48) | KDM4EKMT2APOLBALDH1A1HPGD | |
| SCHEMBL28980160 | 0.72 | KDM4E (0.45) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL28080769 | 0.72 | KDM4E (0.45) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL27176541 | 0.70 | ALDH1A1 (0.49) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL29156685 | 0.69 | KMT2A (0.53) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL30744883 | 0.69 | KMT2A (0.53) | KDM4EKMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL13199349 | 0.69 | PIN1 (0.50) | KDM4EKMT2APOLBALDH1A1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543081-B | Preparation method of 1-difluoroalkylisoquinoline | 四川理工学院 | 2020-02-18 | — | — | CN | disclosed |