⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832358 | 0.88 | PDK2 (0.34) | — | |
| SCHEMBL2836335 | 0.87 | BRD9 (0.30) | — | |
| SCHEMBL2834363 | 0.86 | BRD9 (0.34) | — | |
| SCHEMBL2836329 | 0.83 | NPC1 (0.40) | — | |
| SCHEMBL2834947 | 0.82 | DDX3X (0.36) | — | |
| SCHEMBL2841614 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL2834359 | 0.81 | NPC1 (0.39) | — | |
| SCHEMBL2836109 | 0.81 | KMT2A (0.40) | — | |
| SCHEMBL2833844 | 0.81 | NPC1 (0.39) | — | |
| SCHEMBL6204817 | 0.81 | NOTUM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | claimed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | claimed |
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | disclosed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | disclosed |