Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834359 | 0.93 | NPC1 (0.39) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL1573784 | 0.92 | NPC1 (0.39) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2842333 | 0.90 | MEN1 (0.39) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2834363 | 0.89 | BRD9 (0.34) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2837070 | 0.87 | ESR1 (0.40) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2841614 | 0.86 | KDM4E (0.32) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2838740 | 0.86 | RECQL (0.37) | NPC1RAB9AHPGDL3MBTL1RECQL | |
| SCHEMBL2834947 | 0.86 | DDX3X (0.36) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL2836109 | 0.85 | KMT2A (0.40) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL2835883 | 0.85 | NPC1 (0.32) | NPC1RAB9AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | claimed |
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | disclosed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | UNG, DDT, UMPS | NPC1 4643/4885RAB9A 2151/4885HPGD 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.