Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357968 | 1.00 | MTNR1A (0.65) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL23944947 | 0.88 | MTNR1B (0.61) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL23944988 | 0.88 | MTNR1B (0.61) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL340075 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL12056685 | 0.85 | MTNR1A (0.67) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL12394492 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL340076 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL30892245 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL11917773 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BABCB11SIGMAR1USP2 | |
| SCHEMBL13985221 | 0.85 | MTNR1A (0.72) | MTNR1AMTNR1BABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818720-A | Melatonin (MT1/MT2) receptor agonist, preparation method and application thereof | 上海阳帆医药科技有限公司 | 2020-02-21 | — | — | CN | disclosed |