Hexane

Hexane

SCHEMBL28362010

CCCCCC.Cc1ccc(C=O)cc1C

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
ALDH1A3 P47895 6/20 0.43
CYP2A6 P11509 1/20 0.41
ALDH3A1 P30838 5/20 0.41
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PTGS2 P35354 1/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
FDPS P14324 1/20 0.37
TUBB1 Q9H4B7 1/20 0.36
HIF1A Q16665 1/20 0.36
EPAS1 Q99814 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTGER4 P35408 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98097 0.87 CYP2A6 (0.52) ALDH1A1ALDH1A3CYP2A6TSHRKDM4E
SCHEMBL29350085 0.87 CYP2A6 (0.52) ALDH1A1ALDH1A3CYP2A6TSHRKDM4E
Alcohol SCHEMBL28361987 0.86 ALDH1A1 (0.44) ALDH1A1ALDH1A3CYP2A6ALDH3A1TSHR
SCHEMBL1609646 0.84 CNR1 (0.37) ALDH1A1TSHRKDM4EPTGS2RAB9A
Hydrazine SCHEMBL27345905 0.83 ALDH1A1 (0.48) ALDH1A1ALDH1A3CYP2A6TSHRKDM4E
SCHEMBL1610718 0.82 CNR1 (0.36) TSHRPTGS2TUBB1
SCHEMBL1611000 0.82 CNR1 (0.36) TSHRPTGS2TUBB1
SCHEMBL1610157 0.82 TUBB1 (0.37) ALDH1A1KDM4EPTGS2RAB9ATUBB1
O-Xylene SCHEMBL7770810 0.81 ALDH1A1 (0.48) ALDH1A1ALDH1A3CYP2A6TSHRKDM4E
SCHEMBL9226581 0.79 ALDH1A3 (0.38) ALDH1A1ALDH1A3CYP2A6ALDH3A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110742070-A Application of 3, 4-dimethylbenzaldehyde 西南林业大学 2020-02-04 CN disclosed