Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177707 | 0.82 | MEN1 (0.47) | TLR8ALDH1A1TYRKDM4EMEN1 | |
| SCHEMBL28098354 | 0.79 | MEN1 (0.51) | TLR8ALDH1A1GAAERAP1TYR | |
| SCHEMBL22679783 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GAAERAP1TYRKDM4E | |
| SCHEMBL17699137 | 0.77 | ATM (0.35) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL5822562 | 0.77 | TYR (0.46) | TLR8ALDH1A1GAAERAP1TYR | |
| SCHEMBL5829949 | 0.77 | TLR8 (0.45) | TLR8TYRMEN1KMT2ATP53 | |
| SCHEMBL8225761 | 0.77 | MEN1 (0.46) | TLR8ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22672783 | 0.76 | TDP1 (0.44) | ALDH1A1GAAERAP1KDM4EHPGD | |
| SCHEMBL18076729 | 0.76 | TLR8 (0.47) | TLR8ALDH1A1GAATYRKDM4E | |
| SCHEMBL3747524 | 0.75 | MEN1 (0.45) | TLR8ALDH1A1GAATYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565408-B | 1,5, 9-trisubstituted coronene compound and synthesis method thereof | 上海大学 | 2019-12-06 | — | — | CN | disclosed |