Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166774 | 0.89 | AKR1B1 (0.36) | MAPTLMNAGUSBPGR | |
| SCHEMBL28363145 | 0.85 | SSTR5 (0.33) | KDM4EALDH1A1SMN1; SMN2LMNASSTR5 | |
| SCHEMBL22714339 | 0.84 | MAPT (0.36) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL29438153 | 0.84 | MAPT (0.36) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL29438157 | 0.84 | MAPT (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21635547 | 0.84 | MAPT (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21635540 | 0.83 | ESPL1 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25061603 | 0.81 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL25061604 | 0.79 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL22714353 | 0.77 | CA1 (0.41) | MAPTALDH1A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818699-B | Isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-110818699-A | Isoxazoline compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-02-21 | — | — | CN | disclosed |