Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166774 | 0.86 | AKR1B1 (0.36) | ESPL1MAPTLMNAHTTPGR | |
| SCHEMBL29438153 | 0.86 | MAPT (0.36) | ESPL1MAPTLMNAHTTPGR | |
| SCHEMBL22714339 | 0.86 | MAPT (0.36) | ESPL1MAPTLMNAHTTPGR | |
| SCHEMBL28363043 | 0.83 | MAPT (0.37) | MAPTLMNAPGRALDH1A1MEN1 | |
| SCHEMBL29438166 | 0.82 | CA1 (0.41) | ESPL1MAPTLMNAHTTPGR | |
| SCHEMBL22714353 | 0.82 | CA1 (0.41) | ESPL1MAPTLMNAHTTPGR | |
| SCHEMBL21635547 | 0.81 | MAPT (0.38) | MAPTLMNACA1CA2RAB9A | |
| SCHEMBL29438157 | 0.81 | MAPT (0.38) | MAPTLMNACA1CA2RAB9A | |
| SCHEMBL21635544 | 0.80 | CA1 (0.32) | CA1CA2CRBN | |
| SCHEMBL25061603 | 0.79 | MAPT (0.38) | MAPTAKR1B1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202821-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-01-21 | — | — | US | disclosed |
| CN-118084888-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-113874368-B | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-3976603-B1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-15 | — | — | EP | disclosed |
| US-20220227744-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-07-21 | — | — | US | disclosed |
| EP-3976603-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-04-06 | — | — | EP | disclosed |
| CN-113874368-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020239607-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-03 | — | — | WO | disclosed |
| CN-105753853-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-106536517-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | DDX6, OAT, DHX36 | ESPL1 3644/4885MAPT 1284/4885LMNA 4541/4885 |
| US-20220227744-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | ESPL1 4307/4885MAPT 4021/4885LMNA 3760/4885 |
| US-12202821-B2 | Herbicidal compounds | DDT, ACHE, GSTO1 | ESPL1 4307/4885MAPT 4021/4885LMNA 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.