SCHEMBL283633

SCHEMBL283633

CCCC=CNC=CCCC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283632 1.00 TSHR (0.35) TSHRALDH1A1TAS1R3TAS1R1
SCHEMBL1485949 0.91 TSHR (0.30) TSHRALDH1A1
SCHEMBL1485952 0.91 TSHR (0.30) TSHRALDH1A1
SCHEMBL2391716 0.83
SCHEMBL1485591 0.83
SCHEMBL1485589 0.83
SCHEMBL284640 0.81 TSHR (0.41) TSHRALDH1A1
SCHEMBL284641 0.81 TSHR (0.41) TSHRALDH1A1
SCHEMBL284502 0.79 FAAH (0.48) TSHRALDH1A1
SCHEMBL284503 0.79 FAAH (0.48) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624504-A Modified epoxy resin composition and aqueous coating agent 荒川化学工业株式会社 2024-03-01 CN disclosed
US-9976103-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2018-05-22 US disclosed
EP-2513269-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2017-10-25 EP disclosed
US-20150361272-A1 RUST PREVENTIVE OIL COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-12-17 US disclosed
US-9212426-B2 Rust preventive oil composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-12-15 US disclosed
US-9080123-B2 Rust preventive oil composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-07-14 US disclosed
US-20150166474-A1 IONICALLY BONDED SALT HAVING REACTIVE GROUP AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME NIPPON NYUKAZAI CO., LTD. (JP) 2015-06-18 US disclosed
US-20150096463-A1 RUST PREVENTIVE OIL COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-04-09 US disclosed
EP-2738010-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, PROCESS FOR PRODUCING RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, PROCESS FOR PRODUCING RELIEF PRINTING PLATE, AND RELIEF PRINTING PLATE FUJIFILM Corporation (JP) 2014-06-04 EP disclosed
US-20140130693-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, PROCESS FOR PRODUCING RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, PROCESS FOR MAKING RELIEF PRINTING PLATE, AND RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
EP-1633835-A1 LUBRICATING OIL COMPOSITION WITH ANTIWEAR PERFORMANCE THE LUBRIZOL CORPORATION (US) 2006-03-15 EP disclosed
WO-2004113479-A1 LUBRICATING OIL COMPOSITION WITH ANTIWEAR PERFORMANCE THE LUBRIZOL CORPORATION (US) 2004-12-29 WO disclosed
US-20040259743-A1 Lubricating oil composition with antiwear performance THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-23 US disclosed
US-20040198615-A1 Di-secondary alkyl hindered phenol antioxidants THE LUBRIZOL CORPORATION 2004-10-07 US disclosed
EP-1394289-A1 RUST-PREVENTIVE OIL COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2004-03-03 EP disclosed
EP-0206621-B1 PROCESS FOR DISPROPORTIONATING SILANES MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-15 EP disclosed
EP-0206621-A1 Process for disproportionating silanes MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-12-30 EP disclosed
US-4558101-A FROM HYDROCARBON POLYMER CONTAINING OLEFINIC GROUPS WITH HYDROGEN CARBON MONOXIDE AND AMINE USING GROUP 8 METAL CATALYST W. R. GRACE & CO. (US) 1985-12-10 US disclosed
US-4526936-A Reacting polymeric hydrocarbon, primary or secondary amine, carbon monoxide, hydrogen, in the presence of group VIII metal catalyst W. R. GRACE & CO. (US) 1985-07-02 US disclosed
US-4312965-A Process for forming amine/amide containing polymers W. R. GRACE & CO. (US) 1982-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166474-A1 IONICALLY BONDED SALT HAVING REACTIVE GROUP AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME RER1, INTS9, ELP1 TSHR 3957/4885ALDH1A1 1664/4885TAS1R3 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.