Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363566 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL8005268 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL234461 | 0.68 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL15178348 | 0.66 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL537959 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL12848579 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL28012826 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL28013507 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28165224 | 0.64 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL8778393 | 0.64 | MAPT (0.63) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111073866-A | PQQ-sGDH mutant, polynucleotide and application thereof in glucose detection | 英科隆生物技术（杭州）有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-105331591-B | PQQ-sGDH mutant, polynucleotide and glucose detection device | 英科隆生物技术（杭州）有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-105331590-B | Soluble pyrroloquinoline quinone dependent glucose dehydrogenase mutant with improved glucose specificity, polynucleotide and application thereof | 英科隆生物技术（杭州）有限公司 | 2020-02-28 | — | — | CN | disclosed |